Personalized Medicine: A Call for Action is the third in a series of annual conferences dedicated to explore the opportunities to make Personalized Medicine a reality. It will be a one and a half day conference reflecting a distinctive collaboration between the Harvard Medical School-Partners HealthCare Center for Genetics and Genomics and Harvard Business School. The alliance of these two renowned academic institutions presents an exceptional opportunity to address the integration of medicine and business in accelerating the adoption of Personalized Medicine by bringing together stakeholders, including leaders from pharmaceutical and diagnostics companies, medicine, academia, healthcare providers and payers, regulatory agencies, venture capitalists and the business community.

Participants will engage in a multitude of issues surrounding the obstacles to the adoption of personalized medicine and showcasing evidence that will stimulate these stakeholders to act and overcome these barriers, which will change the practice of medicine by continuing to incorporate genetics and genomics into clinical practice to achieve better outcomes for patients in a cost effective manner. The conference will explore from multiple perspectives how the Personalized Medicine revolution has been put into practice and what is required on the part of physicians, patients, payers, provider organizations, pharmaceutical innovators and the business community to ensure its future success. This conference will be unique in its depth and breadth, in its roster of prestigious speakers from government, academic and industry and in its ability to define and address the issues that confront us as Personalized Medicine becomes even more of a reality.

PROGRAM

      Thursday, November 29

TIME  ACTIVITY
 7:30-8:30  Breakfast & Registration
 
8:15  Welcome
  Raju Kucherlapati, Ph.D., Scientific Director, Harvard Medical School-Partners HealthCare
 Center for Genetics and Genomics, Paul C. Cabot Professor of Genetics, Professor of Medicine,
 Harvard Medical School, Boston, MA

8:25  Keynote Speaker

 M. Kathleen Behrens, Ph.D., General Partner, Consultant, RS Investments, Member, President’s
 Council of Advisors on Science and Technology (PCAST), Ross, CA
PRESENTATION

 Introduction by: Mark J. Levin, Partner, Third Rock Ventures, LLC, Boston, MA
 
9:10  Keynote Speaker

 The Personalized Health Care Challenge

 Michael O. Leavitt, Secretary of Health and Human Services, U.S. Department of Health and
 Human Services, Washington, DC


 Introduction by: James J. Mongan, M.D., Chief Executive Officer, Partners HealthCare System,
 Inc., Boston, MA

 
10:00  Break & Snack
 
 10:45-12:15  Session I: Perspectives from Pharmaceutical and Diagnostics Companies

 Moderator: Richard G. Hamermesh, D.B.A., MBA Class of 1961 Professor of Management
 Practice, Faculty Chair, HBS Healthcare Initiative, Harvard Business School, Cambridge, MA
 
 Seven-minute talks
by each speaker
 Thomas J. Miller, Member, Executive Management Board, Siemens Medical Solutions,
 Erlangen, Germany

 Garry Neil, M.D., President, Johnson & Johnson Pharmaceutical Research & Development,
 Raritan, NJ

 Samuel Broder, M.D., Chief Medical Officer, Celera, Rockville, MD

 Peer M. Schatz, Chief Executive Officer, Qiagen, Germany
PRESENTATION

 Panel Discussion - one hour

12:15  Personalized Medicine Coalition's Third Annual Award for Leadership in Personalized Medicine
 Presentation

  Award Recipient: Ralph Snyderman, M.D., Emeritus Chancellor for Health Affairs and President
 and CEO, Duke University Health System, Chairman and CEO, Proventys, Inc., Durham, NC


 Introduction by: Edward Abrahams, Ph.D., Executive Director, Personalized Medicine Coalition,
 Washington, DC


 Presentation by: Mara G. Aspinall, President, Genzyme Genetics, Genzyme Corporation,
 Westborough, MA

 Plated Lunch

 2:15  Keynote Speaker

 Markets of One: The Pharmaceutical Industry and the Pursuit of Personalized Medicine

 John C. Lechleiter, Ph.D., President and Chief Operating Officer, Eli Lilly and Company,
 Indianapolis, IN
PRESENTATION

 Introduction by: Deborah Dunsire, M.D., President and CEO, Millennium Pharmaceuticals, Inc.,
 Cambridge, MA

 
 3:00  Break & Snack
 
 3:30 - 5:00  Session II: Personalized Medicine: Clinical and Regulatory Issues

 Moderator: Christine Seidman, M.D. Investigator, Howard Hughes Medical Institute, Thomas
 W. Smith Professor of Medicine and Genetics, Harvard Medical School, Director, Cardiovascular
 Genetics Center, Brigham and Women’s Hospital, Boston, MA

 Seven-minute talks
by each speaker
 
 Nadine Cohen, Ph.D., Head of Pharmacogenomics and Senior Research Fellow, Johnson &
 Johnson Pharmaceutical Research & Development East Coast and Europe, Raritan, NJ PRESENTATION

 Mason W. Freeman, M.D., Chief, Lipid Metabolism Unit, Massachusetts General Hospital,
 Harvard Medical School, Boston, MA

 Felix W. Frueh, Ph.D., Associate Director, Genomics, Office of Clinical Pharmacology,
 CDER/FDA, Silver Spring, MD

 Hakan Sakul, Ph.D., Senior Director and Global Head of Diagnostics, Translational and
 Molecular Medicine Group, Worldwide Development, Pfizer Global R&D


 Panel Discussion – one hour
 
5:00  Reception
 
6:30  VIP Dinner at Great Bay Restaurant, Hotel Commonwealth, Boston for Organizing Committee, Speakers,
 Sponsors and other VIP guests
 
 

      Friday, November 30

TIME  ACTIVITY
 7:30-8:30  Breakfast
 
8:30  Keynote Speaker

 Richard M.J. Bohmer, M.D., MBA Class of 1973 Senior Lecturer of Business Administration,
 Harvard Business School, Cambridge, MA


 Introduction by: Norman C. Selby, Senior Managing Director, Perseus, L.L.C., New York, NY (need
 to confirm)
 
9:15-9:45  Keynote Speaker

 Personalized Healthcare: A Way Forward

 Wayne A. Rosenkrans, Jr., Ph.D., President & Chairman, Personalized Medicine Coalition,
 External Relations Director – Evidence-based Medicine and Personalized Healthcare,
 AstraZeneca Pharmaceuticals, Wilmington, DE
PRESENTATION

 Introduction by: Marcia A. Kean, Chief Executive Officer, Feinstein Kean Healthcare, Cambridge,
 MA

 
9:45-11:00  Session III: Who Will Pay for Personalized Medicine?

 Moderator: Edward Abrahams, Ph.D., Executive Director, Personalized Medicine Coalition,
 Washington DC
 
 Seven-minute talks
by each speaker
 Joanne C. Armstrong, M.D., M.P.H., Senior Medical Director for Women's Health and Clinical
 Lead for Genomics, Aetna, Inc., Sugarland, TX
 
 Anthony Miller, Managing Director, Lemhi Ventures, Excelsior, MN
 
 Samuel R. Nussbaum, M.D., Executive Vice President and Chief Medical Officer, Wellpoint, Inc.,
 Indianapolis, IN
 
 Dora L. Hughes, M.D., M.P.H., Health Policy Advisor, Senator Barack Obama, Washington, DC

 
 Panel Discussion - one hour
 
11:00  Break & Snack
 
11:30-12:45  Session IV: What are the Public Policy and IT Issues that will Drive Personalized Medicine?

 Moderator: Gregory Downing, D.O., Ph.D., Program Director, Personalized Health Care, U.S.
 Department of Health and Human Services, Bethesda, MD
 
 Seven-minute talks
by each speaker
 John P. Glaser, Ph.D., Vice President and Chief Information Officer, Partners HealthCare
 System, Inc., Boston, MA
 
 Lawrence J. Lesko, Ph.D., FCP, Director, Office of Clinical Pharmacology, Center for Drug
 Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD
 
 Jeffrey D. Miller, Vice President, WW Health and Life Sciences, WW Public Sector,
 Hewlett-Packard Company, Houston, TX
 
 Sharon F. Terry, M.A., President and CEO, Genetic Alliance, Washington, DC

 
 Panel Discussion - one hour
12:45  Closing
 Raju Kucherlapati, Ph.D., Scientific Director, Harvard Medical School-Partners HealthCare
 Center for Genetics and Genomics, Paul C. Cabot Professor of Genetics, Professor of Medicine,
 Harvard Medical School, Boston, MA

 
1:00  Bag Lunch
 

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ORGANIZING COMMITTEE
Raju Kucherlapati, Ph.D., Chair
Scientific Director
Harvard-Partners Center for Genetics and Genomics
Paul C. Cabot Professor of Genetics
Professor of Medicine
Harvard Medical School

Edward Abrahams, Ph.D.
Executive Director
Personalized Medicine Coalition

Joanne C. Armstrong, M.D.
Senior Medical Director for Women's Health and Clinical Lead for Genomics
Aetna, Inc.

Mara G. Aspinall
President, Genzyme Genetics
Genzyme Corporation
M. Kathleen Behrens Wilsey, Ph.D.
Managing Director
Robertson Stephens & Company

Nadine Cohen, Ph.D.
Head of Pharmacogenomics and
Senior Research Fellow
Johnson & Johnson Pharmaceutical Research and Development, East Coast and Europe

Peter Dworkin
Vice President
Investor Relations and Corporate Communications
Applera Corporation

Richard G. Hamermesh, D.B.A.
MBA Class of 1961 Professor of Management Practice
Harvard Business School
Regina E. Herzlinger, D.B.A.
Nancy R. McPherson Professor of Business Administration
Harvard Business School

Marcia A. Kean
Chief Executive Officer
Feinstein Kean Healthcare

Jeffrey D. Miller
Vice President, Worldwide Health and Life Sciences Industries
Hewlett-Packard Company

Daniel K. Podolsky, M.D.
Chief Academic Officer
Partners HealthCare System, Inc.
Mallinckrodt Professor of Medicine
Harvard Medical School

Eiry W. Roberts, M.D.
Vice President, Project/Program Medical
Eli Lilly and Company
Hakan Sakul, Ph.D.
Senior Director and Global Head of Diagnostics
Translational and Molecular Medicine Group
Worldwide Development

Rick Schlesinger
Director
McKinsey & Company

Christine Seidman, M.D.
Investigator, Howard Hughes Medical Institute
Thomas W. Smith Professor of Medicine and Genetics
Harvard Medical School
Director
Cardiovascular Genetics Center
Brigham and Women's Hospital

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NEWS
"Personalized Medicine: The Future Is (Almost) Now"
Parsons, Heidi. PharmaManufacturing.com.

"Dr. Ralph Snyderman, Chancellor Emeritus, Duke University, and Founder and Chairman..."
Mackenzie, Christine. Reuters. 29 November 2007.

"HHS secretary promotes personalized medicine at Harvard forum"
Cooney, Elizabeth. Boston Globe White Coat Notes. 29 November 2007.

"PCAST Personalized Medicine Draft Report Slated for Spring 2008"
Ray, Turna. GenomeWeb Daily News. 30 November 2007.

"Meeting Offers Vision of Future U.S. Personalized Healthcare System"
Allison, Malorye. Xconomy. 3 December 2007.

"Personalized Medicine - Myth, Pipe Dream or Realizable Promise?"
De, Andy. Andy De Blogspot. 4 December 2007.

"Will HPCGG's New Algorithm Spur Market Adoption of PGx-Based Warfarin Dosing?"
"Lilly Official Proclaims Company 'On Board' With Personalized Medicine."
"PCAST Plans Draft Personalized Medicine Report for Spring; Reimbursement Key Issue."

Ray, Turna. Pharmacogenomics Reporter. 5 December 2007. Subscription required for full content.

"J&J Official Discusses How PGx Helps Company Set 'Realistic Expectations'"
"Dx Shops' Flexibility Will Encourage Co-Development Alliances, Qiagen CEO"
"HHS Chief Leavitt May Leave in '09; Vows To Keep Personalized Medicine enter Stage"

Ray, Turna. Pharmacogenomics Reporter. 12 December 2007. Subscription required for full content.

"Insurers Say More Evidence Needed for Significant Resource Push Behind PGx"
Ray, Turna. Pharmacogenomics Reporter. 19 December 2007. Subscription required for full content.

"Musings on up-close-and-personal medicine"
Parsons, Heidi. PharmaManufacturing.com. 31 December 2007.

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SPONSORS

PLATINUM
Hewlett-Packard

GOLD
McKinsey     Pfizer


SILVER
Applied Biosystems - Celera        AutoGenomics        Millennium   


BRONZE
Genzyme Corp     Goulston & Storrs     Merck     Mintz Levin


OTHER
Affymetrix        Johnson & Johnson        Nixon Peabody        Third Wave Technology   

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Personalized Medicine Conference 2008
This year's Personalized Medicine Conference will take place November 13-14, 2008 at the Joseph B. Martin Conference Center at Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA. Visit our website again in the spring for more details. We hope you can join us!

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  For additional information, please contact Janice Larson at jalarson@partners.org or 617-525-4489

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